Beta-lactam-induced severe neutropenia: a descriptive study
نویسندگان
چکیده
منابع مشابه
Beta lactam monotherapy versus beta lactam-aminoglycoside combination therapy for fever with neutropenia: systematic review and meta-analysis.
OBJECTIVE To compare the effectiveness of beta lactam monotherapy versus beta lactam-aminoglycoside combination therapy in the treatment of patients with fever and neutropenia. DATA SOURCES Medline, Embase, Lilacs, the Cochrane Library, and conference proceedings to 2002. References of included studies and contact with authors. No restrictions on language, year of publication, or publication ...
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Objective(s) Resistance to the new generation of cephalosporins which is mediated by Extended-Spectrum beta-lactamases (ESBLs) has been found among Escherichia coli isolates throughout the world. These resistance genes and their producers, the micro-organisms carrying beta-lactamases, are responsible for serious clinical and therapeutic problems among inpatients and it is necessary to pay more...
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Anti-bacterial drugs have “selective toxicity”, that is they interact with a target present on the bacterial cell, the prokaryote, that is not present in the mammalian host, the eukaryote. For the ß-lactam drugs, this target is the cell wall. Mammalian cells lack cell walls, which for the bacteria are a critically important barrier protecting the organism from not only the vagaries of osmotic s...
متن کاملHypersensitivity to beta-lactam antibiotics: a three-year study.
BACKGROUND Beta-lactams antibiotics (BL) are the most frequent elicitors of allergic drug reactions. The aim of our study was to characterize the patients referred with suspected hypersensitivity (HS) to BL. METHODS Over a three-year period (2011-2013), a total of 234 adult and paediatric patients (pts) with suspected HS to BL were investigated according to the European Network for Drug Aller...
متن کاملBeta lactam hypersensitivities
Background Allergic reactions to drugs are often unpredictable and can lead to serious side effects such as anaphylactic shock. According to the hapten hypothesis, any drug with a molecular weight lower than 1000 daltons cannot induce an immune response by itself and must be bound to a protein. Antigen presenting cells, such as dendritic cells (DC), internalize hapten-protein conjugates and dig...
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ژورنال
عنوان ژورنال: Fundamental & Clinical Pharmacology
سال: 2019
ISSN: 0767-3981
DOI: 10.1111/fcp.12449